4lij

From Proteopedia

proteopedia linkproteopedia link

Template:STRUCTURE 4lij

Contents 1 Crystal structure of a far upstream element (FUSE) binding protein 1 (FUBP1) from Homo sapiens at 1.95 A resolution 2 Function 3 About this Structure 4 Reference

Crystal structure of a far upstream element (FUSE) binding protein 1 (FUBP1) from Homo sapiens at 1.95 A resolution

Function

[FUBP1_HUMAN] Regulates MYC expression by binding to a single-stranded far-upstream element (FUSE) upstream of the MYC promoter. May act both as activator and repressor of transcription.^[1]

About this Structure

4lij is a 3 chain structure. Full crystallographic information is available from OCA.

Reference

1. ↑ Duncan R, Bazar L, Michelotti G, Tomonaga T, Krutzsch H, Avigan M, Levens D. A sequence-specific, single-strand binding protein activates the far upstream element of c-myc and defines a new DNA-binding motif. Genes Dev. 1994 Feb 15;8(4):465-80. PMID:8125259