2qud

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Image:2qud.jpg

2qud, resolution 1.60Å

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PP7 Coat Protein Dimer

Overview

The cocrystal structure of the PP7 bacteriophage coat protein in complex with its translational operator identifies a distinct mode of sequence-specific RNA recognition when compared to the well-characterized MS2 coat protein-RNA complex. The structure reveals the molecular basis of the PP7 coat protein's ability to selectively bind its cognate RNA, and it demonstrates that the conserved beta-sheet surface is a flexible architecture that can evolve to recognize diverse RNA hairpins.

About this Structure

2QUD is a Single protein structure of sequence from Enterobacteria phage p21 with as ligand. Full crystallographic information is available from OCA.

Reference

Structural basis for the coevolution of a viral RNA-protein complex., Chao JA, Patskovsky Y, Almo SC, Singer RH, Nat Struct Mol Biol. 2008 Jan;15(1):103-5. Epub 2007 Dec 9. PMID:18066080

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