4mfd

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Template:STRUCTURE 4mfd

Contents

Structure of the carboxyl transferase domain from Rhizobium etli pyruvate carboxylase with oxalate

Template:ABSTRACT PUBMED 24157795

Function

[Q2K340_RHIEC] Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity).[PIRNR:PIRNR001594]

About this Structure

4mfd is a 4 chain structure with sequence from Rhiec. Full crystallographic information is available from OCA.

Reference

  • Lietzan AD, St Maurice M. Insights into the carboxyltransferase reaction of pyruvate carboxylase from the structures of bound product and intermediate analogs. Biochem Biophys Res Commun. 2013 Oct 22. pii: S0006-291X(13)01738-5. doi:, 10.1016/j.bbrc.2013.10.066. PMID:24157795 doi:http://dx.doi.org/10.1016/j.bbrc.2013.10.066

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