This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4gq0

From Proteopedia

Revision as of 06:04, 4 December 2013 by OCA (Talk | contribs)
Jump to: navigation, search

Template:STRUCTURE 4gq0

Contents

Crystal structure of AKR1B10 complexed with NADP+ and Caffeic acid phenethyl ester

Function

[AK1BA_HUMAN] Acts as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs.[1]

About this Structure

4gq0 is a 1 chain structure with sequence from Human. This structure supersedes the now removed PDB entry 3v9q. Full crystallographic information is available from OCA.

Reference

  1. ↑ Gallego O, Ruiz FX, Ardevol A, Dominguez M, Alvarez R, de Lera AR, Rovira C, Farres J, Fita I, Pares X. Structural basis for the high all-trans-retinaldehyde reductase activity of the tumor marker AKR1B10. Proc Natl Acad Sci U S A. 2007 Dec 26;104(52):20764-9. Epub 2007 Dec 17. PMID:18087047

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4gq0"
Personal tools