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4nof

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Revision as of 07:35, 4 December 2013 by OCA (Talk | contribs)
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Template:STRUCTURE 4nof

Crystal structure of the second Ig domain from mouse Polymeric Immunoglobulin receptor [PSI-NYSGRC-006220]

Function

[PIGR_MOUSE] This receptor binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment (By similarity).

About this Structure

4nof is a 2 chain structure. Full crystallographic information is available from OCA.

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