4bii

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Template:STRUCTURE 4bii

How nature bridges the gap: Crystallographic elucidation of pyridomycin binding to InhA

Template:ABSTRACT PUBMED 24292073

About this Structure

4bii is a 4 chain structure with sequence from Mycobacterium sp. h37rv. Full crystallographic information is available from OCA.

Reference

  • Hartkoorn RC, Pojer F, Read JA, Gingell H, Neres J, Horlacher OP, Altmann KH, Cole ST. Pyridomycin bridges the NADH- and substrate-binding pockets of the enoyl reductase InhA. Nat Chem Biol. 2013 Dec 1. doi: 10.1038/nchembio.1405. PMID:24292073 doi:http://dx.doi.org/10.1038/nchembio.1405

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