4l5f
From Proteopedia
Crystal Structure of DENV1-E106 Fab bound to DENV-1 Envelope protein DIII
Function
[Q8BE40_9FLAV] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS026470_004_099774]
About this Structure
4l5f is a 3 chain structure with sequence from [1] and Mus musculus. Full crystallographic information is available from OCA.
Categories: Mus musculus | CSGID, Center for Structural Genomics of Infectious Diseases. | Edeling, M A. | Fremont, D H. | Nelson, C A. | Antibody | Antibody epitope | Envelope | Fab | Immune system | Infectious disease | National institute of allergy and infectious disease | Neutralizing | Niaid | Viral protein | Virus
