4i74

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Template:STRUCTURE 4i74

Crystal structure of the Trypanosoma brucei Inosine-Adenosine-Guanosine nucleoside hydrolase in complex with compound UAMC-00312 and allosterically inhibited by a Ni2+ ion

Template:ABSTRACT PUBMED 23897478

About this Structure

4i74 is a 1 chain structure with sequence from Tryb2. Full crystallographic information is available from OCA.

Reference

  • Giannese F, Berg M, Van der Veken P, Castagna V, Tornaghi P, Augustyns K, Degano M. Structures of purine nucleosidase from Trypanosoma brucei bound to isozyme-specific trypanocidals and a novel metalorganic inhibitor. Acta Crystallogr D Biol Crystallogr. 2013 Aug;69(Pt 8):1553-66. doi:, 10.1107/S0907444913010792. Epub 2013 Jul 20. PMID:23897478 doi:http://dx.doi.org/10.1107/S0907444913010792

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