4jgx

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Template:STRUCTURE 4jgx

Contents

The Structure of Sterol Carrier Protein 2 from the Yeast Yarrowia Lipolytica

Template:ABSTRACT PUBMED 24241823

Function

[SCP2_YARLI] May play a role in the transport of fatty acids. Binds fatty acids and fatty acyl-CoAs including palmitic acid, oleic acid, cis-parinaric acid and palmitoyl-CoA (in vitro).[1] [2]

About this Structure

4jgx is a 2 chain structure. Full crystallographic information is available from OCA.

Reference

  • De Berti FP, Capaldi S, Ferreyra R, Burgardt N, Acierno JP, Klinke S, Monaco HL, Ermacora MR. The crystal structure of sterol carrier protein 2 from Yarrowia lipolytica and the evolutionary conservation of a large, non-specific lipid-binding cavity. J Struct Funct Genomics. 2013 Dec;14(4):145-53. doi: 10.1007/s10969-013-9166-6., Epub 2013 Nov 17. PMID:24241823 doi:http://dx.doi.org/10.1007/s10969-013-9166-6
  1. Ferreyra RG, Burgardt NI, Milikowski D, Melen G, Kornblihtt AR, Dell' Angelica EC, Santome JA, Ermacora MR. A yeast sterol carrier protein with fatty-acid and fatty-acyl-CoA binding activity. Arch Biochem Biophys. 2006 Sep 15;453(2):197-206. Epub 2006 Jul 21. PMID:16890184 doi:http://dx.doi.org/10.1016/j.abb.2006.06.024
  2. Dell'Angelica EC, Ermacora MR, Santome JA. Purification and partial characterization of a fatty acid-binding protein from the yeast, Yarrowia lipolytica. Biochem Mol Biol Int. 1996 Jun;39(3):439-45. PMID:8828794

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