4kzi
From Proteopedia
Contents |
Crystal Structure of TR3 LBD in complex with DPDO
Function
[NR4A1_HUMAN] Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3' (By similarity). May inhibit NF-kappa-B transactivation of IL2.[1]
About this Structure
4kzi is a 2 chain structure. Full crystallographic information is available from OCA.
Reference
- ↑ Harant H, Lindley IJ. Negative cross-talk between the human orphan nuclear receptor Nur77/NAK-1/TR3 and nuclear factor-kappaB. Nucleic Acids Res. 2004 Oct 5;32(17):5280-90. Print 2004. PMID:15466594 doi:10.1093/nar/gkh856
Categories: Cai, Q. | Chen, H. | Li, A. | Li, F. | Lin, T. | Tian, X. | Wang, W. | Wang, Y. | Wu, Q. | Xing, Y. | Zhang, Q. | Orphan nuclear receptor | Transcription