Neuroligin

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Crystal Structure of human Neuroligin 3be8

Neuroligins (NLGN) are a family of postsynaptic proteins which bind to the presynaptic Neurexin (NRXN) to form a complex which attaches neurons. The NLGN family contains 4 members which are numbered 1 to 4. See Neurodevelopmental Disorders.

For Structural Analysis of Neuroligin, See: Neuroligin-Neurexin Interaction

1 3D Structures of Neuroligin
- 1.1 NLGN
- 1.2 NLGN+NRXN

3D Structures of Neuroligin

Update February 2013

NLGN

3bl8 - mNLGN-2 cholinesterase domain – mouse
3be8 - hNLGN-4 cholinesterase domain – human
3bix - rNLGN-1 cholinesterase domain - rat

NLGN+NRXN

2xb6, 2wqz – hNLGN-4 cholinesterase domain+NRXN-1β LNS domain
3b3q - mNLGN-4 cholinesterase domain+NRXN-1β LNS domain
3biw - rNLGN-1 cholinesterase domain+NRXN-1β LNS domain
3vkf - rNLGN-1 cholinesterase domain + bNRXN-1β LNS domain