4i6y

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Template:STRUCTURE 4i6y

Contents 1 3-hydroxy-3-methyl (HMG) Coenzyme A Reductase bound to R-Mevalonate 2 Function 3 About this Structure 4 See Also 5 Reference

3-hydroxy-3-methyl (HMG) Coenzyme A Reductase bound to R-Mevalonate

Template:ABSTRACT PUBMED 23802607

Function

[MVAA_PSEMV] P.mevalonii can use mevalonate as sole carbon source. With this enzyme mevalonate is deacetylated to HMG-CoA.

About this Structure

4i6y is a 2 chain structure with sequence from 'pseudomonas mevalonii'. Full crystallographic information is available from OCA.

See Also

• HMG-CoA Reductase

Reference

• Steussy CN, Critchelow CJ, Schmidt TJ, Min JK, Wrensford LV, Burgner JW, Rodwell VW, Stauffacher CV. A novel role for CoA during hydride transfer in 3-hydroxy-3-methylglutaryl-coenzyme A reductase. Biochemistry. 2013 Jun 26. PMID:23802607 doi:10.1021/bi400335g