4br2

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Template:STRUCTURE 4br2

Contents

rat NTPDase2 in complex with Ca UMPPNP

Template:ABSTRACT PUBMED 23830739

Function

[ENTP2_RAT] In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Hydrolyzes ADP only to a marginal extent.

About this Structure

4br2 is a 1 chain structure with sequence from Buffalo rat. Full crystallographic information is available from OCA.

Reference

  • Zebisch M, Krauss M, Schafer P, Lauble P, Strater N. Crystallographic Snapshots along the Reaction Pathway of Nucleoside Triphosphate Diphosphohydrolases. Structure. 2013 Jul 2. pii: S0969-2126(13)00200-1. doi:, 10.1016/j.str.2013.05.016. PMID:23830739 doi:10.1016/j.str.2013.05.016

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