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4hdg
From Proteopedia
Contents |
Crystal Structure of viral RdRp in complex with GTP
Template:ABSTRACT PUBMED 24293643
Function
[G3LHD9_9FLAV] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS000336_004_099774]
About this Structure
4hdg is a 2 chain structure. Full crystallographic information is available from OCA.
Reference
- Surana P, Satchidanandam V, Nair DT. RNA-dependent RNA polymerase of Japanese encephalitis virus binds the initiator nucleotide GTP to form a mechanistically important pre-initiation state. Nucleic Acids Res. 2013 Nov 28. PMID:24293643 doi:http://dx.doi.org/10.1093/nar/gkt1106
