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4ipp

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Revision as of 08:22, 15 January 2014 by OCA (Talk | contribs)
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Template:STRUCTURE 4ipp

tRNA-guanine-transglycosylase (TGT) mutant V262D APO-Structure

Function

[TGT_ZYMMO] Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).[HAMAP-Rule:MF_00168]

About this Structure

4ipp is a 1 chain structure. Full crystallographic information is available from OCA.

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OCA

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