2md7

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Template:STRUCTURE 2md7

Contents

NMR structure of human Sp140 PHD finger trans conformer

Template:ABSTRACT PUBMED 24267382

Function

[SP140_HUMAN] Component of the nuclear body, also known as nuclear domain 10, PML oncogenic domain, and KR body. May be involved in the pathogenesis of acute promyelocytic leukemia and viral infection.

About this Structure

2md7 is a 1 chain structure with sequence from Human. Full experimental information is available from OCA.

Reference

  • Zucchelli C, Tamburri S, Quilici G, Palagano E, Berardi A, Saare M, Peterson P, Bachi A, Musco G. Structure of human Sp140 PHD finger: an atypical fold interacting with Pin1. FEBS J. 2014 Jan;281(1):216-31. doi: 10.1111/febs.12588. Epub 2013 Nov 25. PMID:24267382 doi:http://dx.doi.org/10.1111/febs.12588

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OCA

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