3ctz

From Proteopedia

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Template:STRUCTURE 3ctz

Contents 1 Structure of human cytosolic X-prolyl aminopeptidase 2 Function 3 About this Structure 4 See Also 5 Reference

Structure of human cytosolic X-prolyl aminopeptidase

Template:ABSTRACT PUBMED 18515364

Function

[XPP1_HUMAN] Contributes to the degradation of bradykinin. Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Arg-Pro-Pro.

About this Structure

3ctz is a 1 chain structure. Full crystallographic information is available from OCA.

See Also

• Aminopeptidase

Reference

• Li X, Lou Z, Li X, Zhou W, Ma M, Cao Y, Geng Y, Bartlam M, Zhang XC, Rao Z. Structure of human cytosolic X-prolyl aminopeptidase: a double Mn(II)-dependent dimeric enzyme with a novel three-domain subunit. J Biol Chem. 2008 Aug 15;283(33):22858-66. doi: 10.1074/jbc.M710274200. Epub 2008, May 30. PMID:18515364 doi:http://dx.doi.org/10.1074/jbc.M710274200