3w68

From Proteopedia

proteopedia linkproteopedia link

Template:STRUCTURE 3w68

Contents 1 Crystal structure of mouse alpha-tocopherol transfer protein in complex with alpha-tocopherol and phosphatidylinositol-(4,5)-bisphosphate 2 Function 3 About this Structure 4 Reference

Crystal structure of mouse alpha-tocopherol transfer protein in complex with alpha-tocopherol and phosphatidylinositol-(4,5)-bisphosphate

Template:ABSTRACT PUBMED 23599266

Function

[TTPA_MOUSE] Binds alpha-tocopherol and enhances its transfer between separate membranes (By similarity).

About this Structure

3w68 is a 4 chain structure with sequence from Lk3 transgenic mice. Full crystallographic information is available from OCA.

Reference

• Kono N, Ohto U, Hiramatsu T, Urabe M, Uchida Y, Satow Y, Arai H. Impaired alpha-TTP-PIPs Interaction Underlies Familial Vitamin E Deficiency. Science. 2013 Apr 18. PMID:23599266 doi:10.1126/science.1233508