4l55

From Proteopedia

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Template:STRUCTURE 4l55

Contents 1 X-ray structure of the adduct between bovine pancreatic ribonuclease and AziRu 2 Function 3 About this Structure 4 Reference

X-ray structure of the adduct between bovine pancreatic ribonuclease and AziRu

Template:ABSTRACT PUBMED 24093479

Function

[RNAS1_BOVIN] Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single stranded and double stranded RNA.^[1]

About this Structure

4l55 is a 2 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.

Reference

• Vergara A, Russo Krauss I, Montesarchio D, Paduano L, Merlino A. Investigating the ruthenium metalation of proteins: X-ray structure and Raman microspectroscopy of the complex between RNase A and AziRu. Inorg Chem. 2013 Oct 7;52(19):10714-6. doi: 10.1021/ic401494v. Epub 2013 Sep 16. PMID:24093479 doi:http://dx.doi.org/10.1021/ic401494v

1. ↑ delCardayre SB, Ribo M, Yokel EM, Quirk DJ, Rutter WJ, Raines RT. Engineering ribonuclease A: production, purification and characterization of wild-type enzyme and mutants at Gln11. Protein Eng. 1995 Mar;8(3):261-73. PMID:7479688