2xvo

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Template:STRUCTURE 2xvo

Contents

SSO1725, a protein involved in the CRISPR/Cas pathway

Template:ABSTRACT PUBMED 22227115

Function

[CMR7B_SULSO] CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA) (By similarity).

About this Structure

2xvo is a 4 chain structure with sequence from Atcc 35091. Full crystallographic information is available from OCA.

Reference

  • Zhang J, Rouillon C, Kerou M, Reeks J, Brugger K, Graham S, Reimann J, Cannone G, Liu H, Albers SV, Naismith JH, Spagnolo L, White MF. Structure and mechanism of the CMR complex for CRISPR-mediated antiviral immunity. Mol Cell. 2012 Feb 10;45(3):303-13. doi: 10.1016/j.molcel.2011.12.013. Epub 2012 , Jan 5. PMID:22227115 doi:http://dx.doi.org/10.1016/j.molcel.2011.12.013

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