3ecs

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Template:STRUCTURE 3ecs

Contents

Crystal structure of human eIF2B alpha

Template:ABSTRACT PUBMED 19631657

Disease

[EI2BA_HUMAN] Cree leukoencephalopathy;Late infantile CACH syndrome;Ovarioleukodystrophy. The disease is caused by mutations affecting the gene represented in this entry.

Function

[EI2BA_HUMAN] Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.

About this Structure

3ecs is a 8 chain structure with sequence from Human. Full crystallographic information is available from OCA.

See Also

Reference

  • Hiyama TB, Ito T, Imataka H, Yokoyama S. Crystal structure of the alpha subunit of human translation initiation factor 2B. J Mol Biol. 2009 Oct 2;392(4):937-51. Epub 2009 Jul 23. PMID:19631657 doi:10.1016/j.jmb.2009.07.054

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