4lpa

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Template:STRUCTURE 4lpa

Contents

Crystal structure of a Cdc6 phosphopeptide in complex with Cks1

Template:ABSTRACT PUBMED 24186063

Function

[CKS1_YEAST] Binds to the catalytic subunit of the cyclin dependent kinase (CDC28) and is essential for its biological function.

About this Structure

4lpa is a 4 chain structure with sequence from Baker's yeast. Full crystallographic information is available from OCA.

Reference

  • McGrath DA, Balog ER, Koivomagi M, Lucena R, Mai MV, Hirschi A, Kellogg DR, Loog M, Rubin SM. Cks confers specificity to phosphorylation-dependent CDK signaling pathways. Nat Struct Mol Biol. 2013 Dec;20(12):1407-14. doi: 10.1038/nsmb.2707. Epub 2013, Nov 3. PMID:24186063 doi:http://dx.doi.org/10.1038/nsmb.2707

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