4c6p

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Template:STRUCTURE 4c6p

Contents

Crystal structure of the dihydroorotase domain of human CAD C1613S mutant in apo-form at pH 7.0

Template:ABSTRACT PUBMED 24332717

Function

[PYR1_HUMAN] This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase).

About this Structure

4c6p is a 1 chain structure. Full crystallographic information is available from OCA.

Reference

  • Grande-Garcia A, Lallous N, Diaz-Tejada C, Ramon-Maiques S. Structure, Functional Characterization, and Evolution of the Dihydroorotase Domain of Human CAD. Structure. 2013 Dec 10. pii: S0969-2126(13)00428-0. doi:, 10.1016/j.str.2013.10.016. PMID:24332717 doi:http://dx.doi.org/10.1016/j.str.2013.10.016

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OCA

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