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3zlf

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Template:STRUCTURE 3zlf

Contents

Structure of group A Streptococcal enolase K312A mutant

Function

[ENO_STRP6] Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. Binds plasminogen when expressed on the bacterial cell surface, potentially allowing the bacterium to acquire surface-associated proteolytic activity, which in turn contributes to tissue invasion and virulence.[1]

About this Structure

3zlf is a 4 chain structure. Full crystallographic information is available from OCA.

Reference

  1. ↑ Pancholi V, Fischetti VA. alpha-enolase, a novel strong plasmin(ogen) binding protein on the surface of pathogenic streptococci. J Biol Chem. 1998 Jun 5;273(23):14503-15. PMID:9603964

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