4nfm

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Template:STRUCTURE 4nfm

Contents 1 Human tau tubulin kinase 1 (TTBK1) 2 Function 3 About this Structure 4 Reference

Human tau tubulin kinase 1 (TTBK1)

Function

[TTBK1_HUMAN] Serine/threonine kinase which is able to phosphorylate TAU on serine, threonine and tyrosine residues. Induces aggregation of TAU.^[1]

About this Structure

4nfm is a 1 chain structure. Full crystallographic information is available from OCA.

Reference

1. ↑ Sato S, Cerny RL, Buescher JL, Ikezu T. Tau-tubulin kinase 1 (TTBK1), a neuron-specific tau kinase candidate, is involved in tau phosphorylation and aggregation. J Neurochem. 2006 Sep;98(5):1573-84. PMID:16923168 doi:JNC4059