4m4l

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Template:STRUCTURE 4m4l

Contents

The structure of Cu T6 bovine insulin

Template:ABSTRACT PUBMED 24419384

Function

[INS_BOVIN] Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.

About this Structure

4m4l is a 4 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.

Reference

  • Frankaer CG, Mossin S, Stahl K, Harris P. Towards accurate structural characterization of metal centres in protein crystals: the structures of Ni and Cu T6 bovine insulin derivatives. Acta Crystallogr D Biol Crystallogr. 2014 Jan;70(Pt 1):110-22. doi:, 10.1107/S1399004713029040. Epub 2013 Dec 24. PMID:24419384 doi:http://dx.doi.org/10.1107/S1399004713029040

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