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3mwr

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Template:STRUCTURE 3mwr

Contents

Crystal structure of ribonuclease A tandem enzymes and their interaction with the cytosolic ribonuclease inhibitor

Template:ABSTRACT PUBMED 21134128

Function

[RNAS1_BOVIN] Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single stranded and double stranded RNA.[1]

About this Structure

3mwr is a 1 chain structure with sequence from Bovin. Full crystallographic information is available from OCA.

See Also

Reference

  • Arnold U, Leich F, Neumann P, Lilie H, Ulbrich-Hofmann R. Crystal structure of RNase A tandem enzymes and their interaction with the cytosolic ribonuclease inhibitor. FEBS J. 2011 Jan;278(2):331-40. doi: 10.1111/j.1742-4658.2010.07957.x., Epub 2010 Dec 6. PMID:21134128 doi:10.1111/j.1742-4658.2010.07957.x
  1. ↑ delCardayre SB, Ribo M, Yokel EM, Quirk DJ, Rutter WJ, Raines RT. Engineering ribonuclease A: production, purification and characterization of wild-type enzyme and mutants at Gln11. Protein Eng. 1995 Mar;8(3):261-73. PMID:7479688

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