2m32

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Template:STRUCTURE 2m32

Contents

Alpha-1 integrin I-domain in complex with GLOGEN triple helical peptide

Template:ABSTRACT PUBMED 24187131

Function

[ITA1_HUMAN] Integrin alpha-1/beta-1 is a receptor for laminin and collagen. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen.

About this Structure

2m32 is a 4 chain structure with sequence from Human. Full experimental information is available from OCA.

Reference

  • Chin YK, Headey SJ, Mohanty B, Patil R, McEwan PA, Swarbrick JD, Mulhern TD, Emsley J, Simpson JS, Scanlon MJ. The structure of integrin alpha1I domain in complex with a collagen-mimetic peptide. J Biol Chem. 2013 Dec 27;288(52):36796-809. doi: 10.1074/jbc.M113.480251. Epub, 2013 Nov 1. PMID:24187131 doi:http://dx.doi.org/10.1074/jbc.M113.480251

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OCA

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