2mcw

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Template:STRUCTURE 2mcw

Contents

Solid-state NMR structure of piscidin 3 in aligned 3:1 phosphatidylcholine/phosphoglycerol lipid bilayers

Template:ABSTRACT PUBMED 24410116

Function

[PISC3_MORCS] Exhibits broad-spectrum antimicrobial activity against both Gram-positive and Gram-negative bacteria. Has hemolytic activity.

About this Structure

2mcw is a 1 chain structure. Full experimental information is available from OCA.

Reference

  • Perrin BS Jr, Tian Y, Fu R, Grant CV, Chekmenev EY, Wieczorek WE, Dao AE, Hayden RM, Burzynski CM, Venable RM, Sharma M, Opella SJ, Pastor RW, Cotten ML. High-Resolution Structures and Orientations of Antimicrobial Peptides Piscidin 1 and Piscidin 3 in Fluid Bilayers Reveal Tilting, Kinking, and Bilayer Immersion. J Am Chem Soc. 2014 Jan 22. PMID:24410116 doi:http://dx.doi.org/10.1021/ja411119m

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OCA

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