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4is9

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Template:STRUCTURE 4is9

Contents

Crystal Structure of the Escherichia coli LpxC/L-161,240 complex

Template:ABSTRACT PUBMED 24117400

Function

[D5CV28_ECOKI] Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity).[HAMAP-Rule:MF_00388][SAAS:SAAS004463_004_013136]

About this Structure

4is9 is a 2 chain structure with sequence from Ecoki. Full crystallographic information is available from OCA.

Reference

  • Lee CJ, Liang X, Gopalaswamy R, Najeeb J, Ark ED, Toone EJ, Zhou P. Structural Basis of the Promiscuous Inhibitor Susceptibility of E. coli LpxC. ACS Chem Biol. 2013 Oct 11. PMID:24117400 doi:http://dx.doi.org/10.1021/cb400067g

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OCA

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