4kwb

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Template:STRUCTURE 4kwb

Contents

Structure of signal peptide peptidase A with C-termini bound in the active sites: insights into specificity, self-processing and regulation

Template:ABSTRACT PUBMED 24228759

Function

[SPPA_BACSU] Digestion of cleaved signal peptides (By similarity). Required for efficient processing of precursors under conditions of hyper-secretion.

About this Structure

4kwb is a 8 chain structure with sequence from Bacsu. Full crystallographic information is available from OCA.

Reference

  • Nam SE, Paetzel M. Structure of signal peptide peptidase A with C-termini bound in the active sites: insights into specificity, self-processing, and regulation. Biochemistry. 2013 Dec 10;52(49):8811-22. doi: 10.1021/bi4011489. Epub 2013 Nov, 25. PMID:24228759 doi:http://dx.doi.org/10.1021/bi4011489

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