3ikr

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Template:STRUCTURE 3ikr

Contents

Crystal structure of alpha 1-4 mannobiose bound trimeric human lung surfactant protein D

Template:ABSTRACT PUBMED 19799916

Function

[SFTPD_HUMAN] Contributes to the lung's defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.

About this Structure

3ikr is a 3 chain structure with sequence from Human. Full crystallographic information is available from OCA.

Reference

  • Shrive AK, Martin C, Burns I, Paterson JM, Martin JD, Townsend JP, Waters P, Clark HW, Kishore U, Reid KB, Greenhough TJ. Structural characterisation of ligand-binding determinants in human lung surfactant protein D: influence of Asp325. J Mol Biol. 2009 Dec 11;394(4):776-88. Epub 2009 Sep 30. PMID:19799916 doi:10.1016/j.jmb.2009.09.057

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OCA

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