4bqk

From Proteopedia

Revision as of 17:13, 19 February 2014 by OCA (Talk | contribs)
Jump to: navigation, search

Template:STRUCTURE 4bqk

Contents

rice importin_alpha : VirD2NLS complex

Function

[IMA1A_ORYSJ] Functions in nuclear protein import. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Promotes docking of import substrates to the nuclear envelope.[1] [2] [VIRD2_AGRT5] Tumor formation by A.tumefaciens involves the transfer and integration of a defined segment (T-DNA) of Ti plasmid DNA into the plant nuclear genome. The virD operon encodes a site-specific endonuclease that cleaves at a unique site within both 24 bp direct repeats flanking the T-DNA.

About this Structure

4bqk is a 4 chain structure. Full crystallographic information is available from OCA.

Reference

  • Chang CW, Williams SJ, Counago RM, Kobe B. Structural Basis of Interaction of Bipartite Nuclear Localization Signal from Agrobacterium VirD2 with Rice Importin-alpha Mol Plant. 2014 Feb 6. PMID:24503158 doi:http://dx.doi.org/10.1093/mp/ssu014
  1. ↑ Jiang CJ, Imamoto N, Matsuki R, Yoneda Y, Yamamoto N. Functional characterization of a plant importin alpha homologue. Nuclear localization signal (NLS)-selective binding and mediation of nuclear import of nls proteins in vitro. J Biol Chem. 1998 Sep 11;273(37):24083-7. PMID:9727027
  2. ↑ Jiang CJ, Shoji K, Matsuki R, Baba A, Inagaki N, Ban H, Iwasaki T, Imamoto N, Yoneda Y, Deng XW, Yamamoto N. Molecular cloning of a novel importin alpha homologue from rice, by which constitutive photomorphogenic 1 (COP1) nuclear localization signal (NLS)-protein is preferentially nuclear imported. J Biol Chem. 2001 Mar 23;276(12):9322-9. Epub 2000 Dec 20. PMID:11124253 doi:http://dx.doi.org/10.1074/jbc.M006430200

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4bqk"
Personal tools