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4cmv
From Proteopedia
Contents |
Crystal structure of Rv3378c
Template:ABSTRACT PUBMED 24516143
Function
[TUBOL_MYCTU] Catalyzes the PP-removal from tuberculosinyl diphosphate to produce both tubercilosinol and isotuberculosinol. Can also use labdadienyl diphosphates, copalyl diphosphate (CDP), ent-CDP and syn-CDP in vitro.
About this Structure
4cmv is a 2 chain structure. Full crystallographic information is available from OCA.
Reference
- Layre E, Lee HJ, Young DC, Jezek Martinot A, Buter J, Minnaard AJ, Annand JW, Fortune SM, Snider BB, Matsunaga I, Rubin EJ, Alber T, Moody DB. Molecular profiling of Mycobacterium tuberculosis identifies tuberculosinyl nucleoside products of the virulence-associated enzyme Rv3378c. Proc Natl Acad Sci U S A. 2014 Feb 10. PMID:24516143 doi:http://dx.doi.org/10.1073/pnas.1315883111
