4j2e

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Template:STRUCTURE 4j2e

Contents

RB69 DNA Polymerase L415M Ternary Complex

Template:ABSTRACT PUBMED 23921641

Function

[DPOL_BPR69] This polymerase possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single stranded DNA in the 3'- to 5'-direction.

About this Structure

4j2e is a 3 chain structure. Full crystallographic information is available from OCA.

Reference

  • Xia S, Wood M, Bradley MJ, De La Cruz EM, Konigsberg WH. Alteration in the cavity size adjacent to the active site of RB69 DNA polymerase changes its conformational dynamics. Nucleic Acids Res. 2013 Oct;41(19):9077-89. doi: 10.1093/nar/gkt674. Epub 2013, Aug 5. PMID:23921641 doi:http://dx.doi.org/10.1093/nar/gkt674

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