4ofd

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Template:STRUCTURE 4ofd

Contents

Crystal Structure of mouse Neph1 D1-D2

Template:ABSTRACT PUBMED 24485456

Function

[KIRR1_MOUSE] Plays a significant role in the normal development and function of the glomerular permeability. Is a signaling protein that needs the presence of TEC kinases to fully trans-activate the transcription factor AP-1.[1]

About this Structure

4ofd is a 2 chain structure. Full crystallographic information is available from OCA.

Reference

  • Ozkan E, Chia PH, Wang RR, Goriatcheva N, Borek D, Otwinowski Z, Walz T, Shen K, Garcia KC. Extracellular Architecture of the SYG-1/SYG-2 Adhesion Complex Instructs Synaptogenesis. Cell. 2014 Jan 30;156(3):482-94. doi: 10.1016/j.cell.2014.01.004. PMID:24485456 doi:http://dx.doi.org/10.1016/j.cell.2014.01.004
  1. Donoviel DB, Freed DD, Vogel H, Potter DG, Hawkins E, Barrish JP, Mathur BN, Turner CA, Geske R, Montgomery CA, Starbuck M, Brandt M, Gupta A, Ramirez-Solis R, Zambrowicz BP, Powell DR. Proteinuria and perinatal lethality in mice lacking NEPH1, a novel protein with homology to NEPHRIN. Mol Cell Biol. 2001 Jul;21(14):4829-36. PMID:11416156 doi:http://dx.doi.org/10.1128/MCB.21.14.4829-4836.2001

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