4npl

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Template:STRUCTURE 4npl

Crystal structure of Zebrafish ALKBH5 in complex with alpha-ketoglutarate

Function

[ALKB5_DANRE] Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N(6)-methyladenosine (m(6)A) RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes. Requires molecular oxygen, alpha-ketoglutarate and iron (By similarity).

About this Structure

4npl is a 2 chain structure. Full crystallographic information is available from OCA.

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