3l3h

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Template:STRUCTURE 3l3h

Contents 1 X-ray crystal structure of the F6A mutant of influenza A acid polymerase epitope PA224 bound to murine H2-Db MHC 2 Function 3 About this Structure 4 See Also 5 Reference

X-ray crystal structure of the F6A mutant of influenza A acid polymerase epitope PA224 bound to murine H2-Db MHC

Template:ABSTRACT PUBMED 20212169

Function

[HA11_MOUSE] Involved in the presentation of foreign antigens to the immune system. [Q17TI0_9INFA] Implicated in endonuclease cleavage of capped RNA primers. Displays an elongation factor activity in viral RNA synthesis. Dispensable for viral transcription, but not replication (By similarity).[SAAS:SAAS001009_004_020464] [B2MG_MOUSE] Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.

About this Structure

3l3h is a 3 chain structure with sequence from Lk3 transgenic mice. Full crystallographic information is available from OCA.

See Also

• Beta-2 microglobulin
• Major histocompatibility complex

Reference

• Theodossis A, Guillonneau C, Welland A, Ely LK, Clements CS, Williamson NA, Webb AI, Wilce JA, Mulder RJ, Dunstone MA, Doherty PC, McCluskey J, Purcell AW, Turner SJ, Rossjohn J. Constraints within major histocompatibility complex class I restricted peptides: presentation and consequences for T-cell recognition. Proc Natl Acad Sci U S A. 2010 Mar 23;107(12):5534-9. Epub 2010 Mar 8. PMID:20212169 doi:10.1073/pnas.1000032107