4n3m

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Template:STRUCTURE 4n3m

Contents

Joint neutron/X-ray structure of urate oxidase in complex with 8-azaxanthine

Template:ABSTRACT PUBMED 24466188

Function

[URIC_ASPFL] Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.

About this Structure

4n3m is a 1 chain structure. Full crystallographic information is available from OCA.

Reference

  • Oksanen E, Blakeley MP, El-Hajji M, Ryde U, Budayova-Spano M. The neutron structure of urate oxidase resolves a long-standing mechanistic conundrum and reveals unexpected changes in protonation. PLoS One. 2014 Jan 23;9(1):e86651. doi: 10.1371/journal.pone.0086651. eCollection, 2014 Jan 23. PMID:24466188 doi:http://dx.doi.org/10.1371/journal.pone.0086651

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OCA

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