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4azm

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Revision as of 15:22, 3 March 2014 by OCA (Talk | contribs)
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Template:STRUCTURE 4azm

Contents

Human epidermal fatty acid-binding protein (FABP5) in complex with the inhibitor BMS-309413

Template:ABSTRACT PUBMED 24531463

Function

[FABP5_HUMAN] High specificity for fatty acids. Highest affinity for C18 chain length. Decreasing the chain length or introducing double bonds reduces the affinity. May be involved in keratinocyte differentiation.

About this Structure

4azm is a 2 chain structure with sequence from Human. Full crystallographic information is available from OCA.

Reference

  • Sanson B, Wang T, Sun J, Wang L, Kaczocha M, Ojima I, Deutsch D, Li H. Crystallographic study of FABP5 as an intracellular endocannabinoid transporter. Acta Crystallogr D Biol Crystallogr. 2014 Feb;70(Pt 2):290-8. doi:, 10.1107/S1399004713026795. Epub 2014 Jan 29. PMID:24531463 doi:http://dx.doi.org/10.1107/S1399004713026795

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OCA

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