4azr

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Template:STRUCTURE 4azr

Contents

Human epidermal fatty acid-binding protein (FABP5) in complex with the endocannabinoid anandamide

Template:ABSTRACT PUBMED 24531463

Function

[FABP5_HUMAN] High specificity for fatty acids. Highest affinity for C18 chain length. Decreasing the chain length or introducing double bonds reduces the affinity. May be involved in keratinocyte differentiation.

About this Structure

4azr is a 2 chain structure with sequence from Human. Full crystallographic information is available from OCA.

Reference

  • Sanson B, Wang T, Sun J, Wang L, Kaczocha M, Ojima I, Deutsch D, Li H. Crystallographic study of FABP5 as an intracellular endocannabinoid transporter. Acta Crystallogr D Biol Crystallogr. 2014 Feb;70(Pt 2):290-8. doi:, 10.1107/S1399004713026795. Epub 2014 Jan 29. PMID:24531463 doi:http://dx.doi.org/10.1107/S1399004713026795

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OCA

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