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1f76

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Template:STRUCTURE 1f76

Contents

ESCHERICHIA COLI DIHYDROOROTATE DEHYDROGENASE

Template:ABSTRACT PUBMED 12220493

Function

[PYRD_ECOLI] Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.[1]

About this Structure

1f76 is a 4 chain structure with sequence from 9bact. Full crystallographic information is available from OCA.

Reference

  • Norager S, Jensen KF, Bjornberg O, Larsen S. E. coli dihydroorotate dehydrogenase reveals structural and functional distinctions between different classes of dihydroorotate dehydrogenases. Structure. 2002 Sep;10(9):1211-23. PMID:12220493
  1. ↑ Bjornberg O, Gruner AC, Roepstorff P, Jensen KF. The activity of Escherichia coli dihydroorotate dehydrogenase is dependent on a conserved loop identified by sequence homology, mutagenesis, and limited proteolysis. Biochemistry. 1999 Mar 9;38(10):2899-908. PMID:10074342 doi:http://dx.doi.org/10.1021/bi982352c

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