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3u2b

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Template:STRUCTURE 3u2b

Contents

Structure of the Sox4 HMG domain bound to DNA

Template:ABSTRACT PUBMED 22181698

Function

[SOX4_MOUSE] Transcriptional activator that binds with high affinity to the T-cell enhancer motif 5'-AACAAAG-3' motif.

About this Structure

3u2b is a 3 chain structure with sequence from Lk3 transgenic mice. Full crystallographic information is available from OCA.

Reference

  • Jauch R, Ng CK, Narasimhan K, Kolatkar PR. Crystal structure of the Sox4 HMG/DNA complex suggests a mechanism for the positional interdependence in DNA recognition. Biochem J. 2011 Dec 19. PMID:22181698 doi:10.1042/BJ20111768

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