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4duq

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Template:STRUCTURE 4duq

Contents

The Structure of Ca2+-loaded S100A2 at 1.3A resolution

Template:ABSTRACT PUBMED 22394450

Function

[S10A2_HUMAN] May act as a modulator against excess calcium accumulation in normal human mammary epithelial cells. May also play a role in suppressing tumor cell growth.[1]

About this Structure

4duq is a 2 chain structure with sequence from Human. This structure supersedes the now removed PDB entry 3n22. Full crystallographic information is available from OCA.

See Also

Reference

  1. ↑ Lee SW, Tomasetto C, Swisshelm K, Keyomarsi K, Sager R. Down-regulation of a member of the S100 gene family in mammary carcinoma cells and reexpression by azadeoxycytidine treatment. Proc Natl Acad Sci U S A. 1992 Mar 15;89(6):2504-8. PMID:1372446

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