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3whb
From Proteopedia
Contents |
Crystal structure of FadR from Bacillus subtilis, a transcriptional regulator involved in the regulation of fatty acid degradation
Template:ABSTRACT PUBMED 24356978
Function
[FADR_BACSU] Transcriptional regulator in fatty acid degradation. Represses transcription of genes required for fatty acid transport and beta-oxidation, including acdA, fadA, fadB, fadE, fadF, fadG, fadH, fadM, fadN, lcfA and lcfB. Binding of FadR to DNA is specifically inhibited by long chain fatty acyl-CoA compounds of 14-20 carbon atoms in length.
About this Structure
3whb is a 2 chain structure. Full crystallographic information is available from OCA.
Reference
- Fujihashi M, Nakatani T, Hirooka K, Matsuoka H, Fujita Y, Miki K. Structural characterization of a ligand-bound form of Bacillus subtilis FadR involved in the regulation of fatty acid degradation. Proteins. 2013 Dec 20. doi: 10.1002/prot.24496. PMID:24356978 doi:http://dx.doi.org/10.1002/prot.24496
