4lz3

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Template:STRUCTURE 4lz3

Contents

F95H Epi-isozizaene synthase: Complex with Mg, inorganic pyrophosphate and benzyl triethyl ammonium cation

Template:ABSTRACT PUBMED 24517311

Function

[CYC1_STRCO] Catalyzes the cyclization of farnesyl diphosphate (FPP) to the sesquiterpene epi-isozizaene.

About this Structure

4lz3 is a 1 chain structure. Full crystallographic information is available from OCA.

Reference

  • Li R, Chou WK, Himmelberger JA, Litwin KM, Harris GG, Cane DE, Christianson DW. Reprogramming the Chemodiversity of Terpenoid Cyclization by Remolding the Active Site Contour of epi-Isozizaene Synthase. Biochemistry. 2014 Feb 25;53(7):1155-68. doi: 10.1021/bi401643u. Epub 2014 Feb, 11. PMID:24517311 doi:http://dx.doi.org/10.1021/bi401643u

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