4cot

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Template:STRUCTURE 4cot

Contents

The importance of the Abn2 calcium cluster in the endo-1,5- arabinanase activity from Bacillus subtilis

Template:ABSTRACT PUBMED 24549757

Function

[EABN2_BACSU] Involved in the degradation of arabinan and is a key enzyme in the complete degradation of the plant cell wall. Catalyzes the internal cleavage of alpha-(1->5)-L-arabinofuranosyl residues of the alpha-1,5-L-arabinan to produce arabino-oligosaccharides and L-arabinose. It is also active toward linear branched sugar beet arabinan, and pectin from apple.[1] [2]

About this Structure

4cot is a 1 chain structure. Full crystallographic information is available from OCA.

Reference

  • McVey CE, Ferreira MJ, Correia B, Lahiri S, de Sanctis D, Carrondo MA, Lindley PF, de Sa Nogueira I, Soares CM, Bento I. The importance of the Abn2 calcium cluster in the endo-1,5-arabinanase activity from Bacillus subtilis. J Biol Inorg Chem. 2014 Feb 19. PMID:24549757 doi:http://dx.doi.org/10.1007/s00775-014-1105-x
  1. Inacio JM, de Sa-Nogueira I. Characterization of abn2 (yxiA), encoding a Bacillus subtilis GH43 arabinanase, Abn2, and its role in arabino-polysaccharide degradation. J Bacteriol. 2008 Jun;190(12):4272-80. Epub 2008 Apr 11. PMID:18408032 doi:http://dx.doi.org/JB.00162-08
  2. De Sanctis D, Inacio JM, Lindley PF, De Sa-Nogueira I, Bento I. New evidence for the role of calcium in the glycosidase reaction of GH43 arabinanases. FEBS J. 2010 Sep 10. doi: 10.1111/j.1742-4658.2010.07870.x. PMID:20883454 doi:10.1111/j.1742-4658.2010.07870.x

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