4ojt

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Template:STRUCTURE 4ojt

Contents

Helicobacter pylori MTAN complexed with S-ribosylhomocysteine and adenine

Template:ABSTRACT PUBMED 23148563

Function

[MTNN_HELPJ] Responsible for cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH) (By similarity).

About this Structure

4ojt is a 1 chain structure. Full crystallographic information is available from OCA.

Reference

  • Mishra V, Ronning DR. Crystal structures of the Helicobacter pylori MTAN enzyme reveal specific interactions between S-adenosylhomocysteine and the 5'-alkylthio binding subsite. Biochemistry. 2012 Dec 4;51(48):9763-72. doi: 10.1021/bi301221k. Epub 2012 Nov, 20. PMID:23148563 doi:http://dx.doi.org/10.1021/bi301221k

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OCA

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