4k8b

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Template:STRUCTURE 4k8b

Crystal structure of HCV NS3/4A protease complexed with inhibitor

Template:ABSTRACT PUBMED 24144444

About this Structure

4k8b is a 4 chain structure. Full crystallographic information is available from OCA.

Reference

  • Laplante SR, Nar H, Lemke CT, Jakalian A, Aubry N, Kawai SH. Ligand bioactive conformation plays a critical role in the design of drugs that target the hepatitis C virus NS3 protease. J Med Chem. 2014 Mar 13;57(5):1777-89. doi: 10.1021/jm401338c. Epub 2013 Nov 8. PMID:24144444 doi:http://dx.doi.org/10.1021/jm401338c

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