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Introduction to Hormone-Sensitive Lipase

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Hormone-Sensitive Lipase

Hormone-sensitive lipases represent a class of esterases within the hydrolase class that catalyzes the cleavage of ester bonds in fatty acid molecules when stimulated by a hormone. The activation and mobilization of these hormone-sensitive lipases can be triggered by various catecholamines and inhibited by insulin. [1]


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Structure of Hormone-Sensitive Lipase

Hormone-Sensitive Lipase from 3dnm

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Inhibition of Hormone-Sensitive Lipase

Medical Relevance of Hormone-Sensitive Lipase

Additional Pages about Hormone-Sensitive Lipase

References

  1. Nam KH, Kim MY, Kim SJ, Priyadarshi A, Kwon ST, Koo BS, Yoon SH, Hwang KY. Structural and functional analysis of a novel hormone-sensitive lipase from a metagenome library. Proteins. 2009 Mar;74(4):1036-40. PMID:19089974 doi:http://dx.doi.org/10.1002/prot.22313
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